BDBM68261 Microlactone, 15f trans

SMILES Oc1cc(O)c2c(CC(=O)CCC\C=C\CCOC2=O)c1Cl

InChI Key InChIKey=AQKZYZQONWDDLS-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 68261   

TargetATP-dependent molecular chaperone HSP82(Baker's yeast)
University of Nottingham

LigandPNGBDBM68261(Microlactone, 15f trans)
Affinity DataIC50: 3.50E+3nMAssay Description:A colorimetric assay for the release of inorganic phosphate upon hydrolysis of ATP was used to determine the potency of Hsp 90 inhibitor against enzy...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetATP-dependent molecular chaperone HSP82(Baker's yeast)
University of Nottingham

LigandPNGBDBM68261(Microlactone, 15f trans)
Affinity DataIC50: 590nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetATP-dependent molecular chaperone HSP82(Baker's yeast)
University of Nottingham

LigandPNGBDBM68261(Microlactone, 15f trans)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)