BDBM68260 Microlactone, 15f cis

SMILES Oc1cc(O)c2c(CC(=O)CCC\C=C/CCOC2=O)c1Cl

InChI Key InChIKey=AQKZYZQONWDDLS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 68260   

TargetATP-dependent molecular chaperone HSP82(Baker's yeast)
University of Nottingham

LigandPNGBDBM68260(Microlactone, 15f cis)
Affinity DataIC50: 2.40E+3nMAssay Description:A colorimetric assay for the release of inorganic phosphate upon hydrolysis of ATP was used to determine the potency of Hsp 90 inhibitor against enzy...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent molecular chaperone HSP82(Baker's yeast)
University of Nottingham

LigandPNGBDBM68260(Microlactone, 15f cis)
Affinity DataIC50: 500nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent molecular chaperone HSP82(Baker's yeast)
University of Nottingham

LigandPNGBDBM68260(Microlactone, 15f cis)
Affinity DataIC50: 850nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed