BDBM665895 US20240116922, Comparator 2B

SMILES CC(C)Oc1nc2nc(cn2cc1C(=O)Nc1cnn2cc(C)cnc12)C12CC(C)(C1)OC2

InChI Key InChIKey=DEQCXGYERMCXNL-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 665895   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Ma

US Patent
LigandPNGBDBM665895(US20240116922, Comparator 2B)
Affinity DataIC50: 0.800nMAssay Description:The 2-hour 1 mM ATP Biochemical Assay employed a MesoScale Detection (MSD) format. The kinase reaction was based on the IRAK4 phosphorylation of a bi...More data for this Ligand-Target Pair
In DepthDetails
US Patent
PDB3D3D Structure (crystal)