BDBM65515 76343-93-6::LAT-A::LatA::Latrunculin A
SMILES C[C@H]1CC[C@@H]2C[C@H](C[C@@](O)(O2)[C@@H]2CSC(=O)N2)OC(=O)\C=C(C)/CC\C=C\C=C/1
InChI Key InChIKey=DDVBPZROPPMBLW-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 65515
Affinity DataIC50: 70nMT: 2°CAssay Description:Saturated ACT1 wild type (WT) as well as engineered ACT1 R183K (R183K) and ACT1 R335K (R335K) cultures were adjusted to 10 OD600 and 3 uL of serial 1...More data for this Ligand-Target Pair
Affinity DataIC50: 110nMT: 2°CAssay Description:Saturated ACT1 wild type (WT) as well as engineered ACT1 R183K (R183K) and ACT1 R335K (R335K) cultures were adjusted to 10 OD600 and 3 uL of serial 1...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMT: 2°CAssay Description:Saturated ACT1 wild type (WT) as well as engineered ACT1 R183K (R183K) and ACT1 R335K (R335K) cultures were adjusted to 10 OD600 and 3 uL of serial 1...More data for this Ligand-Target Pair
TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Human)
University of Louisana
Curated by ChEMBL
University of Louisana
Curated by ChEMBL
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of hypoxia-induced HIF1 activation in human T47D cells by cell based reporter gene assayMore data for this Ligand-Target Pair
TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Human)
University of Louisana
Curated by ChEMBL
University of Louisana
Curated by ChEMBL
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of 1,10-phenanthroline-induced HIF1 activation in human T47D cells by cell based reporter gene assayMore data for this Ligand-Target Pair