BDBM636322 US20230365546, Compound 105

SMILES CC(C)C(=O)Nc1nc2cc(ccn2n1)-c1ccc2n(C)cc(C(=O)NC(C)c3ccccc3)c2c1

InChI Key InChIKey=XYAYQAFPZOGMAA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 636322   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Origiant Pharmaceutical

US Patent
LigandPNGBDBM636322(US20230365546, Compound 105)
Affinity DataIC50: 55nMAssay Description:In vitro kinase assays were conducted using Kinase Profiler services provided by Eurofins. The experimental method was as follows: the small molecule...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Origiant Pharmaceutical

US Patent
LigandPNGBDBM636322(US20230365546, Compound 105)
Affinity DataIC50: 35nMAssay Description:Inhibition of RIPK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed