BDBM554652 US11339144, Compound I-102

SMILES CN(C)C(=O)c1ccc(Cn2c(cc3c(Br)cc(Sc4ccc(Cl)c(Cl)c4)cc23)C(O)=O)cc1

InChI Key InChIKey=MJYFVDNMTKLGTH-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 554652   

TargetGTP-binding protein Rheb(Human)
Navitor Pharmaceuticals

US Patent
LigandPNGBDBM554652(US11339144, Compound I-102)
Affinity DataIC50: 1.00E+4nMAssay Description:For the Rheb-dependent in vitro kinase assay, HA-GST-Rheb was first loaded with GTP-γ-S (Millipore #20-176) by incubating 600 ng/μL Rheb wi...More data for this Ligand-Target Pair
In DepthDetails
US Patent
PDB3D3D Structure (crystal)