BDBM544457 (2S)-3-Phenyl-2-[(3R)-pyrrolidin-3-yl]propanoic acid; hydrochloride::US11286249, Example 17

SMILES OC(=O)[C@@H](Cc1ccccc1)[C@H]1CCNC1

InChI Key InChIKey=OSTNIMGVYREMID-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 544457   

TargetApolipoprotein(a)(Human)
Eli Lilly

US Patent
LigandPNGBDBM544457((2S)-3-Phenyl-2-[(3R)-pyrrolidin-3-yl]propanoic ac...)
Affinity DataIC50: 152nMAssay Description:The in vitro binding affinity of compounds to the intended target human Apo(a) protein is tested in a competitive binding assay. Human Apo(a) protein...More data for this Ligand-Target Pair
In DepthDetails
US Patent
PDB3D3D Structure (crystal)