BDBM519305 US11116757, No. F2

SMILES Cc1nn(c2NC(=O)C(NC(=O)c3cccc(C)c3)C(c12)c1ccc(C)cc1)-c1ccccc1

InChI Key InChIKey=WMAFBTHYXHDENE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 519305   

TargetDCN1-like protein 1/NEDD8-conjugating enzyme Ubc12(Human)
Memorial Sloan Kettering Cancer Center

US Patent
LigandPNGBDBM519305(US11116757, No. F2)
Affinity DataIC50: 3.71E+3nMAssay Description:The TR-FRET assay is illustrated in FIG. 3A and FIG. 3B. The TR-FRET assay cocktail was prepared by mixing 50 nM Biotin-DCN1P, 20 nM AlexaFluor488 UB...More data for this Ligand-Target Pair
In DepthDetails
US Patent