BDBM50608081 CHEMBL5270364

SMILES Cc1cc(=O)n(nc1-c1ccccc1)C1CCNCC1

InChI Key InChIKey=TWZULJZXADJJPI-UHFFFAOYSA-N

Data  3 Kd

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50608081   

TargetHistone-lysine N-methyltransferase NSD3(Human)
University of S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50608081(CHEMBL5270364)
Affinity DataKd:  7.31E+5nMAssay Description:Binding affinity to recombinant human NSD3 PWWP1 domain (247 to 398 residues) by SPR analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase NSD3(Human)
University of S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50608081(CHEMBL5270364)
Affinity DataKd:  7.31E+5nMAssay Description:Inhibition of NSD3 PWWP1 domain (unknown origin) assessed as inhibition constant by SPR analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase NSD3(Human)
University of S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50608081(CHEMBL5270364)
Affinity DataKd:  6.50E+5nMAssay Description:Binding affinity to human NSD3 PWWP1 domain assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)