BDBM50607287 CHEMBL5219727

SMILES COc1cc(OC)c(cc1Cl)-n1c(=O)cc([nH]c1=O)C(F)(F)F

InChI Key InChIKey=GGXGVBQCYFQKID-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50607287   

TargetBranched-chain-amino-acid aminotransferase, cytosolic(Human)
Bayer Pharma

Curated by ChEMBL

LigandBDBM50607287(CHEMBL5219727)Copy SMILESCopy InChI

Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of N-terminal his-tagged human recombinant BCAT1 expressed in Escherichia coli BL21(DE3) cells using leucine and alpha-KG as substrate in ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidPDBSimilars

In DepthDetails
Copy BDB DOIPubMedPDB3D Structure (crystal)
Copy reaction URL

TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Human)
Bayer Pharma

Curated by ChEMBL

LigandBDBM50607287(CHEMBL5219727)Copy SMILESCopy InChI

Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant BCAT2 using leucine and alpha-KG as substrate in presence of NADH by fluorescence assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidPDBSimilars

In DepthDetails
Copy BDB DOIPubMed
Copy reaction URL