BDBM50606921 CHEMBL5219485

SMILES [#6]-[#6]-[#6@H](-[#6]-[#6](=O)-c1cc2cc(-[#8]-[#6])c(-[#8]-[#6])cc2[se;v2]1)-[#6](-[#8])=O

InChI Key InChIKey=BWQHPFYQJHFPHN-SECBINFHSA-N

Data  4 EC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50606921   

TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50606921(CHEMBL5219485)
Affinity DataEC50:  9.24E+3nMAssay Description:Agonist activity at STING in human THP-1 cells harboring IRF-inducible luciferase reporter construct assessed as increase in relative fluorescence un...More data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetStimulator of interferon genes protein(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50606921(CHEMBL5219485)
Affinity DataEC50:  5.71E+3nMAssay Description:Agonist activity at STING in mouse RAW264.7 cells harboring IRF-inducible luciferase reporter construct assessed as increase in relative fluorescence...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50606921(CHEMBL5219485)
Affinity DataEC50:  5.19E+3nMAssay Description:Agonist activity at STING in cGAS knockout human THP-1 cells harboring IRF-inducible luciferase reporter construct assessed as increase in relative f...More data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50606921(CHEMBL5219485)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at STING in STING knockout human THP-1 cells harboring IRF-inducible luciferase reporter construct assessed as increase in relative ...More data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)