BDBM50605457 CHEMBL5183366

SMILES CSc1ncc2cc3cnccc3c(c2n1)[N+](=O)[O-]

InChI Key InChIKey=FAEYQDREFVLABR-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50605457   

TargetSerine/threonine-protein kinase haspin(Human)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605457(CHEMBL5183366)
Affinity DataIC50: 119nMAssay Description:Inhibition of recombinant human Haspin (470 to 798 residues) expressed in bacterial expression system using ARTKQTARKSTGGKAPRKQLA as substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetDual specificity protein kinase CLK1(Mouse)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605457(CHEMBL5183366)
Affinity DataIC50: 221nMAssay Description:Inhibition of recombinant mouse CLK1 expressed in bacteria using GRSRSRSRSRSR as substrate in presence of ATP measured after 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Rat)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605457(CHEMBL5183366)
Affinity DataIC50: 916nMAssay Description:Inhibition of recombinant rat DYRK1A (1 to 499 residues ) expressed in bacterial expression system using KKISGRLSPIMTEQ as substrate measured after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed