BDBM50602502 CHEMBL5190157

SMILES C[C@@H](C1CC1)N1Cc2cc(cc(C)c2C1=O)-c1ccn2nc(N)c(C(=O)N[C@H]3C[C@H](O)C3)c2n1

InChI Key InChIKey=DKTOKFSQYVFDRK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50602502   

LigandPNGBDBM50602502(CHEMBL5190157)
Affinity DataIC50: 46nMAssay Description:Inhibition of PI3Kgamma (unknown origin) in rhMPC1 stimulated human THP-1 cells assessed as reduction in Akt phosphorylation level at Ser473 residue ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50602502(CHEMBL5190157)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of PI3Kgamma (unknown origin) using PIP2 as substrate preincubated for 1 hr followed by substrate addition and measured after 60 mins in p...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50602502(CHEMBL5190157)
Affinity DataIC50: 92nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate preincubated for 1 hr followed by substrate addition and measured after 60 mins in p...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50602502(CHEMBL5190157)
Affinity DataIC50: 83nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2 as substrate preincubated for 1 hr followed by substrate addition and measured after 60 mins in p...More data for this Ligand-Target Pair
In DepthDetails
PubMed