BDBM50601918 LY-3214996::LY3214996::Ly 3214996::Ly3214996::TEMUTERKIB::Temuterkib::[14c]-ly3214996

SMILES Cn1nccc1Nc1nccc(n1)-c1cc2C(=O)N(CCN3CCOCC3)C(C)(C)c2s1

InChI Key InChIKey=JNPRPMBJODOFEC-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50601918   

TargetMitogen-activated protein kinase 1(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50601918(TEMUTERKIB | Temuterkib | Ly 3214996 | Ly3214996 |...)
Affinity DataIC50: 5nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50601918(TEMUTERKIB | Temuterkib | Ly 3214996 | Ly3214996 |...)
Affinity DataIC50: 5nMAssay Description:Inhibition of ERK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 1(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50601918(TEMUTERKIB | Temuterkib | Ly 3214996 | Ly3214996 |...)
Affinity DataKi:  0.0640nMAssay Description:Binding affinity to ERK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50601918(TEMUTERKIB | Temuterkib | Ly 3214996 | Ly3214996 |...)
Affinity DataKi:  0.650nMAssay Description:Binding affinity to ERK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed