BDBM50596962 CHEMBL5196142

SMILES Nc1nc(Oc2ccc(NC(=O)N[C@@H](CCc3ccccc3)C(O)=O)cc2)c2cc[nH]c2n1

InChI Key InChIKey=PCOWASOBSDEANU-UHFFFAOYSA-N

Data  2 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50596962   

TargetTyrosine-protein kinase JAK2(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50596962(CHEMBL5196142)
Affinity DataKd:  327nMAssay Description:Binding affinity to wild type JAK2 JH2 pseudokinase domain (unknown origin) expressed in Sf9 cells and measured upto 30 mins by competitive fluoresce...More data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase JAK2(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50596962(CHEMBL5196142)
Affinity DataKd:  179nMAssay Description:Binding affinity to wild type JAK2 JH2 pseudokinase domain (unknown origin) V617F mutant expressed in Sf9 cells and measured upto 30 mins by competit...More data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)