BDBM50595922 CHEMBL4303389

SMILES C[C@H](Nc1cc(cc(Nc2cnccn2)n1)-c1cnn(C)c1)c1ccc(F)cc1

InChI Key InChIKey=UQTPDWDAYHAZNT-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50595922   

TargetTyrosine-protein kinase JAK2(Human)
Csir-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM50595922(CHEMBL4303389)
Affinity DataIC50: 0.270nMAssay Description:Inhibition of JAK 2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595922(CHEMBL4303389)
Affinity DataIC50: 33nMAssay Description:Inhibition of human JAK1 kinase domain incubated for 1 hrs in the presence of ATP by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Csir-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM50595922(CHEMBL4303389)
Affinity DataIC50: 0.720nMAssay Description:Inhibition of human JAK2 kinase domain incubated for 1 hrs in the presence of ATP by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595922(CHEMBL4303389)
Affinity DataIC50: 39nMAssay Description:Inhibition of human JAK3 kinase domain incubated for 1 hrs in the presence of ATP by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595922(CHEMBL4303389)
Affinity DataIC50: 22nMAssay Description:Inhibition of human TYK2 kinase domain incubated for 1 hrs in the presence of ATP by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed