BDBM50594747 LOXO-305::LY-3527727::LY3527727::Loxo-305::PIRTOBRUTINIB::Pirtobrutinib::RXC-005

SMILES COc1ccc(F)cc1C(=O)NCc1ccc(cc1)-c1nn([C@@H](C)C(F)(F)F)c(N)c1C(N)=O

InChI Key InChIKey=FWZAWAUZXYCBKZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50594747   

TargetTyrosine-protein kinase BTK(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594747(Pirtobrutinib | Loxo-305 | LOXO-305 | LY-3527727 |...)
Affinity DataIC50: 1nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase BTK(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594747(Pirtobrutinib | Loxo-305 | LOXO-305 | LY-3527727 |...)
Affinity DataIC50: 1nMAssay Description:Inhibition of BTK C481S mutant (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed