BDBM50591318 CHEMBL5204196

SMILES C[C@H]1C[C@H](CCO1)N1C(=O)C[C@](C)(NC1=N)c1cccc(Nc2cnc(nc2)C2CC2)c1Cl

InChI Key InChIKey=RUZADINCVKIRSK-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50591318   

TargetPlasmepsin X(Plasmodium falciparum (isolate 3D7))
Ucb

Curated by ChEMBL
LigandPNGBDBM50591318(CHEMBL5204196)
Affinity DataIC50: 9nMAssay Description:Inhibition of Plasmodium falciparum recombinant C-terminal TEV cleavable 8his-tagged PMX by FRET assayMore data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetCathepsin D(Human)
Ucb

Curated by ChEMBL
LigandPNGBDBM50591318(CHEMBL5204196)
Affinity DataIC50: 215nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetRenin(Human)
Ucb

Curated by ChEMBL
LigandPNGBDBM50591318(CHEMBL5204196)
Affinity DataIC50: 2.36E+3nMAssay Description:Inhibition of human reninMore data for this Ligand-Target Pair
In DepthDetails
PubMed