BDBM50590931 CHEMBL5181163

SMILES CC(C)(O)C#Cc1ccc2[nH]cc(-c3ccnc(N)n3)c2c1

InChI Key InChIKey=YYAZUVAPGBAUDQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50590931   

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50590931(CHEMBL5181163)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of human GST tagged PIKFYVE (1493 to end residues) expressed in baculovirus-infected Sf9 cells using PI(3)P:PS as substrate incubated for ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50590931(CHEMBL5181163)
Affinity DataIC50: 21nMAssay Description:Inhibition of PIKFYVE in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTau-tubulin kinase 1(Human)
Biogen

Curated by ChEMBL
LigandPNGBDBM50590931(CHEMBL5181163)
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of GST-tagged TTBK1 (1 to 421) (unknown origin) using DNA Topoisomerase 2-alpha-Thr1342 as substrate incubated for 15 mins followed by ATP...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTau-tubulin kinase 1(Human)
Biogen

Curated by ChEMBL
LigandPNGBDBM50590931(CHEMBL5181163)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TTBK1 in human HEK293T cells incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed