BDBM50586493 CHEMBL5083998::US20240139189, Compound 15

SMILES CC(C)Nc1cc(ncn1)N1CCC2(CC1)CN(CC(=O)N2)c1ccc(CN2CCC(C)(C)CC2)cc1

InChI Key InChIKey=HJOBOVGEKZTYKP-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50586493   

TargetN6-adenosine-methyltransferase catalytic subunit(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50586493(CHEMBL5083998 | US20240139189, Compound 15)
Affinity DataIC50: 330nMAssay Description:Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetN6-adenosine-methyltransferase non-catalytic subunit(Human)
University of Zurich

US Patent
LigandPNGBDBM50586493(CHEMBL5083998 | US20240139189, Compound 15)
Affinity DataIC50: 330nMAssay Description:No details are given in this patent.More data for this Ligand-Target Pair
In DepthDetails
US Patent
PDB3D3D Structure (crystal)