BDBM50585842 CHEMBL5072692

SMILES Cc1c(cccc1-c1ccccc1)-c1nnc(Nc2cccc(CNCCO)c2)o1

InChI Key InChIKey=YBHXMLDVPTWSAS-UHFFFAOYSA-N

Data  2 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50585842   

TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50585842(CHEMBL5072692)
Affinity DataIC50: 2.78E+4nMAssay Description:Inhibition of PD-1/PD-L1 (unknown origin) interaction pre-incubated for 15 mins and measured after 90 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgrammed cell death 1 ligand 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50585842(CHEMBL5072692)
Affinity DataKd:  25nMAssay Description:Binding affinity to human PD-L1 assessed as dissociation constant by micro-scale thermophoresis analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgrammed cell death 1 ligand 1(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50585842(CHEMBL5072692)
Affinity DataKd:  480nMAssay Description:Binding affinity to mouse PD-L1 assessed as dissociation constant by micro-scale thermophoresis analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50585842(CHEMBL5072692)
Affinity DataIC50: 28nMAssay Description:Inhibition of interaction of Fc(IgG1)-Avi)-(Biotin)-fused human PDL1 (19 to 239 residues)/Eu-labeled human PD-1 (25 to 167 residues) expressed in HEK...More data for this Ligand-Target Pair
In DepthDetails
PubMed