BDBM50585390 CHEMBL5089133

SMILES [H][C@]12CC[C@]([H])(CN(C1)c1nc(OC[C@@]34CCCN3C[C@H](F)C4)nc3c(F)c(ncc13)-c1cc(O)cc3ccccc13)N2

InChI Key InChIKey=LRWPFUDCDOHRDC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50585390   

TargetGTPase KRas(Human)
Mirati Therapeutics

Curated by ChEMBL
LigandPNGBDBM50585390(CHEMBL5089133)
Affinity DataIC50: 24nMAssay Description:Inhibition of KRAS G12D mutant in human AGS cells assessed as reduction in ERK phosphorylation measured after 3 hrs by In-Cell Western assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed