BDBM50576 2-(4,5-dihydroxy-2-methyl-phenyl)-6-hydroxy-4-methoxy-benzoic acid::2-(4,5-dihydroxy-2-methylphenyl)-6-hydroxy-4-methoxybenzoic acid::4-methoxy-2-[2-methyl-4,5-bis(oxidanyl)phenyl]-6-oxidanyl-benzoic acid::MLS000877038::SMR000440664::cid_6918469

SMILES COc1cc(O)c(C(O)=O)c(c1)-c1cc(O)c(O)cc1C

InChI Key InChIKey=ADPBTBPPIIKLEH-UHFFFAOYSA-N

Data  1 KI  29 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 32 hits for monomerid = 50576   

TargetPOsterior Segregation(Caenorhabditis elegans)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50576(4-methoxy-2-[2-methyl-4,5-bis(oxidanyl)phenyl]-6-o...)
Affinity DataEC50:  3.10E+4nMAssay Description:Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetInsulin receptor(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50576(4-methoxy-2-[2-methyl-4,5-bis(oxidanyl)phenyl]-6-o...)
Affinity DataIC50: 1.92E+4nMAssay Description:Inhibition of recombinant INSRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAurora kinase A(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50576(4-methoxy-2-[2-methyl-4,5-bis(oxidanyl)phenyl]-6-o...)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of recombinant Aurora AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50576(4-methoxy-2-[2-methyl-4,5-bis(oxidanyl)phenyl]-6-o...)
Affinity DataIC50: 3.44E+4nMAssay Description:Inhibition of recombinant VEGFR3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNUAK family SNF1-like kinase 1(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50576(4-methoxy-2-[2-methyl-4,5-bis(oxidanyl)phenyl]-6-o...)
Affinity DataIC50: 2.27E+4nMAssay Description:Inhibition of recombinant ARK5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 8(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50576(4-methoxy-2-[2-methyl-4,5-bis(oxidanyl)phenyl]-6-o...)
Affinity DataIC50: 3.03E+4nMAssay Description:Inhibition of recombinant COTMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50576(4-methoxy-2-[2-methyl-4,5-bis(oxidanyl)phenyl]-6-o...)
Affinity DataIC50: 3.37E+4nMAssay Description:Inhibition of recombinant TIE2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50576(4-methoxy-2-[2-methyl-4,5-bis(oxidanyl)phenyl]-6-o...)
Affinity DataIC50: 2.85E+4nMAssay Description:Inhibition of recombinant SRCMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50576(4-methoxy-2-[2-methyl-4,5-bis(oxidanyl)phenyl]-6-o...)
Affinity DataIC50: 1.68E+4nMAssay Description:Inhibition of recombinant IGF1RMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFocal adhesion kinase 1(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50576(4-methoxy-2-[2-methyl-4,5-bis(oxidanyl)phenyl]-6-o...)
Affinity DataIC50: 3.44E+4nMAssay Description:Inhibition of recombinant FAKMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50576(4-methoxy-2-[2-methyl-4,5-bis(oxidanyl)phenyl]-6-o...)
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of recombinant B-RAF-V600E mutantMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50576(4-methoxy-2-[2-methyl-4,5-bis(oxidanyl)phenyl]-6-o...)
Affinity DataIC50: 3.44E+4nMAssay Description:Inhibition of recombinant CK2alpha1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50576(4-methoxy-2-[2-methyl-4,5-bis(oxidanyl)phenyl]-6-o...)
Affinity DataIC50: 2.44E+4nMAssay Description:Inhibition of recombinant PLK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PLK4(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50576(4-methoxy-2-[2-methyl-4,5-bis(oxidanyl)phenyl]-6-o...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of recombinant SAKMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50576(4-methoxy-2-[2-methyl-4,5-bis(oxidanyl)phenyl]-6-o...)
Affinity DataIC50: 5.51E+3nMAssay Description:Inhibition of recombinant FLT3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50576(4-methoxy-2-[2-methyl-4,5-bis(oxidanyl)phenyl]-6-o...)
Affinity DataIC50: 2.03E+4nMAssay Description:Inhibition of recombinant PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 4(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50576(4-methoxy-2-[2-methyl-4,5-bis(oxidanyl)phenyl]-6-o...)
Affinity DataIC50: 3.23E+4nMAssay Description:Inhibition of recombinant EPHB4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50576(4-methoxy-2-[2-methyl-4,5-bis(oxidanyl)phenyl]-6-o...)
Affinity DataIC50: 3.37E+4nMAssay Description:Inhibition of recombinant EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50576(4-methoxy-2-[2-methyl-4,5-bis(oxidanyl)phenyl]-6-o...)
Affinity DataIC50: 3.44E+4nMAssay Description:Inhibition of recombinant AKT1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50576(4-methoxy-2-[2-methyl-4,5-bis(oxidanyl)phenyl]-6-o...)
Affinity DataIC50: 1.55E+4nMAssay Description:Inhibition of recombinant CDK4/CycD1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAurora kinase B(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50576(4-methoxy-2-[2-methyl-4,5-bis(oxidanyl)phenyl]-6-o...)
Affinity DataIC50: 3.78E+3nMAssay Description:Inhibition of recombinant Aurora BMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50576(4-methoxy-2-[2-methyl-4,5-bis(oxidanyl)phenyl]-6-o...)
Affinity DataIC50: 1.48E+4nMAssay Description:Inhibition of recombinant METMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50576(4-methoxy-2-[2-methyl-4,5-bis(oxidanyl)phenyl]-6-o...)
Affinity DataIC50: 1.72E+4nMAssay Description:Inhibition of recombinant VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50576(4-methoxy-2-[2-methyl-4,5-bis(oxidanyl)phenyl]-6-o...)
Affinity DataIC50: 3.44E+4nMAssay Description:Inhibition of recombinant ERBB2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50576(4-methoxy-2-[2-methyl-4,5-bis(oxidanyl)phenyl]-6-o...)
Affinity DataIC50: 3.44E+4nMAssay Description:Inhibition of recombinant CDK2/CycAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucose-6-phosphate dehydrogenase-6-phosphogluconolactonase(Plasmodium falciparum 3D7)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50576(4-methoxy-2-[2-methyl-4,5-bis(oxidanyl)phenyl]-6-o...)
Affinity DataIC50: 1.94E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetGlucose-6-phosphate dehydrogenase-6-phosphogluconolactonase(Plasmodium falciparum 3D7)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50576(4-methoxy-2-[2-methyl-4,5-bis(oxidanyl)phenyl]-6-o...)
Affinity DataIC50: 8.00E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50576(4-methoxy-2-[2-methyl-4,5-bis(oxidanyl)phenyl]-6-o...)
Affinity DataIC50: 3.10E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetGlucose-6-phosphate dehydrogenase-6-phosphogluconolactonase(Plasmodium falciparum 3D7)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50576(4-methoxy-2-[2-methyl-4,5-bis(oxidanyl)phenyl]-6-o...)
Affinity DataIC50: 3.75E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetZinc finger protein mex-5(Caenorhabditis elegans)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50576(4-methoxy-2-[2-methyl-4,5-bis(oxidanyl)phenyl]-6-o...)
Affinity DataEC50:  3.00E+5nMAssay Description:Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
LigandPNGBDBM50576(4-methoxy-2-[2-methyl-4,5-bis(oxidanyl)phenyl]-6-o...)
Affinity DataIC50: 4.15E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
LigandPNGBDBM50576(4-methoxy-2-[2-methyl-4,5-bis(oxidanyl)phenyl]-6-o...)
Affinity DataKi:  2.00E+4nMAssay Description:Inhibition of rat brain microsomes nSMase assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails
PubMed