BDBM50575493 Acebilustat::Ctx-4430::EP-501
SMILES OC(=O)c1ccc(CN2C[C@@H]3C[C@H]2CN3Cc2ccc(Oc3ccc(cc3)-c3ncco3)cc2)cc1
InChI Key InChIKey=GERJIEKMNDGSCS-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50575493
Affinity DataIC50: 142nMAssay Description:Inhibition of LTA4H in human whole blood assessed as reduction of calcium ionophore A23187-stimulated LTB4 generation preincubated for 4 hrs followed...More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of LTA4H in human PBMC assessed as reduction of calcium ionophore A23187-stimulated LTB4 generation preincubated for 4 hrs followed by ion...More data for this Ligand-Target Pair
Affinity DataIC50: 4.90nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged LTA4H (unknown origin) expressed in Escherichia coli BL21 DE3 cells at enzyme concentrat...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of LTA4H (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 135nMAssay Description:Inhibition of LTA4H in human blood assessed as LTB4 productionMore data for this Ligand-Target Pair