BDBM50575488 CHEMBL4852381
SMILES N[C@@H](CC(O)=O)Cn1nnc(n1)-c1ccc(Oc2ncc(Cl)cc2F)cc1
InChI Key InChIKey=ZEGMEJVULDALSH-UHFFFAOYSA-N
Data 14 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 50575488
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged LTA4H (unknown origin) expressed in Escherichia coli BL21 DE3 cells at enzyme concentrat...More data for this Ligand-Target Pair
Affinity DataIC50: 167nMAssay Description:Inhibition of LTA4H in human whole blood assessed as reduction of calcium ionophore A23187-stimulated LTB4 generation preincubated for 15 mins follow...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of [3H]dofetilide from recombinant human ERG stably expressed in HEK293 cell membranes measured after 90 mins by microbeta liquid scinti...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of [3H]WIN35428 from recombinant human dopamine transporter by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Nav1.5 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human ERG by manual patch clamp assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERG by Qpatch methodMore data for this Ligand-Target Pair
Affinity DataIC50: 53nMAssay Description:Inhibition of LTA4H in human whole blood assessed as reduction of calcium ionophore A23187-stimulated LTB4 generation preincubated for 4 hrs followed...More data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:Inhibition of LTA4H in human PBMC assessed as reduction of calcium ionophore A23187-stimulated LTB4 generation preincubated for 4 hrs followed by ion...More data for this Ligand-Target Pair
Affinity DataIC50: 0.120nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged LTA4H (unknown origin) expressed in Escherichia coli BL21 DE3 cells at enzyme concentrat...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of LTA4H (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 53nMAssay Description:Inhibition of LTA4H in human blood assessed as LTB4 productionMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of LTA4H (unknown origin) using Arg-AMC as substrate preincubated with compound for 15 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
Affinity DataIC50: 53nMAssay Description:Inhibition of LTA4H in human whole blood assessed as ionophore-stimulated LTB4 release preincubated for 15 mins by competitive immunoassayMore data for this Ligand-Target Pair