BDBM50575257 CHEMBL4856470

SMILES Fc1ccc2OCCc2c1CNc1ncc(NC(=O)c2ccccc2)c2nncn12

InChI Key InChIKey=HNOVSELXQVAOAN-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50575257   

TargetPolycomb protein EED(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50575257(CHEMBL4856470)
Affinity DataIC50: 200nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetPolycomb protein EED(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50575257(CHEMBL4856470)
Affinity DataIC50: 200nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)