BDBM50571039 CHEMBL4877846

SMILES CC(C)n1nc(C)c(c1C)-c1nc2c(ccnc2[nH]1)-c1ccc2[C@@H](CCCCc2c1)NC(=O)c1nc(no1)C(C)(C)C

InChI Key InChIKey=XHKFYFCKCXKVPO-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50571039   

TargetTyrosine-protein kinase BTK(Human)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50571039(CHEMBL4877846)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50571039(CHEMBL4877846)
Affinity DataIC50: 58nMAssay Description:Inhibition of BTK in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50571039(CHEMBL4877846)
Affinity DataIC50: 3nMAssay Description:Inhibition of BTK in human PBMCMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C9(Human)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50571039(CHEMBL4877846)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C19(Human)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50571039(CHEMBL4877846)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50571039(CHEMBL4877846)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human BTKMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Fgr(Human)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50571039(CHEMBL4877846)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of human FGRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50571039(CHEMBL4877846)
Affinity DataIC50: 27nMAssay Description:Inhibition of human SRCMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAurora kinase A(Human)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50571039(CHEMBL4877846)
Affinity DataIC50: 60nMAssay Description:Inhibition of human Aurora-AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMisshapen-like kinase 1(Human)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50571039(CHEMBL4877846)
Affinity DataIC50: 91nMAssay Description:Inhibition of human MINK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase(Rat)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50571039(CHEMBL4877846)
Affinity DataIC50: 11nMAssay Description:Inhibition of BTK in rat whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed