BDBM50569843 CHEMBL4856175

SMILES COc1ccccc1N1CCN(CC1)[C@H]1CCCC[C@@H]1NS(=O)(=O)c1ccccc1

InChI Key InChIKey=OVTXOMMQHRIKGL-UHFFFAOYSA-N

Data  7 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50569843   

TargetMucolipin-1(Human)
Ludwig-Maximilians University

Curated by ChEMBL
LigandPNGBDBM50569843(CHEMBL4856175)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human TRPML1deltaNC-YFP expressed in HEK293 cells preincubated for 10 mins followed by stimulation with ML-SA1 and measured after 10 mi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetMucolipin-1(Human)
Ludwig-Maximilians University

Curated by ChEMBL
LigandPNGBDBM50569843(CHEMBL4856175)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human TRPML1deltaNC-YFP expressed in HEK293 cells preincubated for 10 mins followed by stimulation with ML-SA1 and measured after 10 mi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetMucolipin-2(Human)
Ludwig-Maximilians University

Curated by ChEMBL
LigandPNGBDBM50569843(CHEMBL4856175)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human TRPML2-YFP expressed in HEK293 cells preincubated for 10 mins followed by stimulation with ML-SA1 and measured after 10 mins by F...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMucolipin-3(Human)
Ludwig-Maximilians University

Curated by ChEMBL
LigandPNGBDBM50569843(CHEMBL4856175)
Affinity DataIC50: 2.85E+4nMAssay Description:Inhibition of human TRPML3-YFP expressed in HEK293 cells preincubated for 10 mins followed by stimulation with ML-SA1 and measured after 10 mins by F...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMucolipin-3(Human)
Ludwig-Maximilians University

Curated by ChEMBL
LigandPNGBDBM50569843(CHEMBL4856175)
Affinity DataIC50: 2.85E+4nMAssay Description:Inhibition of human TRPML3-YFP expressed in HEK293 cells preincubated for 10 mins followed by stimulation with ML-SA1 and measured after 10 mins by F...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMucolipin-2(Human)
Ludwig-Maximilians University

Curated by ChEMBL
LigandPNGBDBM50569843(CHEMBL4856175)
Affinity DataEC50:  3.30E+3nMAssay Description:Activation of human TRPML2-YFP expressed in HEK293 cells incubated for 10 mins by Fluo-4 dye calcium imaging based FLIPR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMucolipin-1(Human)
Ludwig-Maximilians University

Curated by ChEMBL
LigandPNGBDBM50569843(CHEMBL4856175)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human TRPML1deltaNC-YFP expressed in HEK293 cells stimulated with ML-SA1 for 200 secs followed by incubation for 200 secs with compound...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetMucolipin-3(Human)
Ludwig-Maximilians University

Curated by ChEMBL
LigandPNGBDBM50569843(CHEMBL4856175)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human TRPML3-YFP expressed in HEK293 cells stimulated with ML-SA1 for 200 secs followed by incubation for 200 secs with compound and me...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed