BDBM50563723 CHEMBL4128865

SMILES Nc1nccc(n1)-c1c(ncn1C1CCN(Cc2ccon2)CC1)-c1ccc(F)cc1

InChI Key InChIKey=XPWHRQHBPRSUAW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50563723   

TargetCasein kinase I isoform delta(Human)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM50563723(CHEMBL4128865)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of wild-type human CK1delta using PLSRTLpSVASLPGL as substrate incubated for 40 mins in presence of ATP by Kinase-Glo luminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCasein kinase I isoform epsilon(Human)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM50563723(CHEMBL4128865)
Affinity DataIC50: 17nMAssay Description:Inhibition of wild-type human CK1epsilon using PLSRTLpSVASLPGL as substrate incubated for 70 mins in presence of ATP by Kinase-Glo luminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed