BDBM50563675 CHEMBL4762791

SMILES O=c1[nH]cc(C2CCCCC2)c2nccn12

InChI Key InChIKey=IRDDESQGXYVSBF-UHFFFAOYSA-N

Data  5 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50563675   

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Institute For Organic Syntheses (Vuos)

Curated by ChEMBL
LigandPNGBDBM50563675(CHEMBL4762791)
Affinity DataIC50: 660nMAssay Description:Inhibition of CDK2/cyclin E (unknown origin) using peptide substrate in presence of [gamma33P]ATP by image analyserMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
Institute For Organic Syntheses (Vuos)

Curated by ChEMBL
LigandPNGBDBM50563675(CHEMBL4762791)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of CDK1/cyclin B (unknown origin) using peptide substrate in presence of [gamma33P]ATP by image analyserMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Institute For Organic Syntheses (Vuos)

Curated by ChEMBL
LigandPNGBDBM50563675(CHEMBL4762791)
Affinity DataIC50: 680nMAssay Description:Inhibition of CDK2/cyclin A2 (unknown origin) using peptide substrate in presence of [gamma33P]ATP by image analyserMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Institute For Organic Syntheses (Vuos)

Curated by ChEMBL
LigandPNGBDBM50563675(CHEMBL4762791)
Affinity DataIC50: 1.43E+4nMAssay Description:Inhibition of CDK4/cyclin D1 (unknown origin) using peptide substrate in presence of [gamma33P]ATP by image analyserMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Institute For Organic Syntheses (Vuos)

Curated by ChEMBL
LigandPNGBDBM50563675(CHEMBL4762791)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK9/cyclin T1 (unknown origin) using peptide substrate in presence of [gamma33P]ATP by image analyserMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Institute For Organic Syntheses (Vuos)

Curated by ChEMBL
LigandPNGBDBM50563675(CHEMBL4762791)
Affinity DataKd:  4.10E+3nMAssay Description:Binding affinity to CDK2 (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)