BDBM50563655 CHEMBL4758206

SMILES CNc1nc(OC2CCCC2)nc2n(Cc3c(F)cccc3F)cnc12

InChI Key InChIKey=AWZRHMXFDZUHLF-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50563655   

TargetTyrosine-protein kinase receptor UFO(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50563655(CHEMBL4758206)
Affinity DataIC50: 794nMAssay Description:Inhibition of GST-tagged AXL (unknown origin) (464 to 485 residues) using Axltide (CKKSRGDYMTMQJG-acid) peptide as substrate preincubated for 30 mins...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50563655(CHEMBL4758206)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of His6/TEV fused-GST-tagged Flt3 (unknown origin) (H564 to S993 residues) using Axltide (CKKSRGDYMTMQJ-acid) peptide as substrate preincu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Mer(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50563655(CHEMBL4758206)
Affinity DataIC50: 126nMAssay Description:Inhibition of 6His/thrombin cleavage site-fused Avi-tagged dephosphorylated MER (unknown origin) (R528 to M999 residues) using Axltide (CKKSRGDYMTMQJ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)