BDBM50563533 CHEMBL4777288

SMILES CC(C)(C)c1ccc(cc1)-c1coc2ccc(nc12)-c1cn[nH]c1

InChI Key InChIKey=OOLXXVMFVSTNLJ-UHFFFAOYSA-N

Data  21 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 21 hits for monomerid = 50563533   

TargetHomeodomain-interacting protein kinase 3(Human)
Masaryk University

Curated by ChEMBL
LigandPNGBDBM50563533(CHEMBL4777288)
Affinity DataIC50: 476nMAssay Description:Inhibition of human recombinant HIPK3 using myelin substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase-like 3(Human)
Masaryk University

Curated by ChEMBL
LigandPNGBDBM50563533(CHEMBL4777288)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CDKL3 (unknown origin) by NanoBRET cellular target engagement assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 11(Human)
Masaryk University

Curated by ChEMBL
LigandPNGBDBM50563533(CHEMBL4777288)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of MLK3 (unknown origin) by NanoBRET cellular target engagement assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 10(Human)
Masaryk University

Curated by ChEMBL
LigandPNGBDBM50563533(CHEMBL4777288)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of MLK2 (unknown origin) by NanoBRET cellular target engagement assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 9(Human)
Masaryk University

Curated by ChEMBL
LigandPNGBDBM50563533(CHEMBL4777288)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of MLK1 (unknown origin) by NanoBRET cellular target engagement assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50563533(CHEMBL4777288)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of DYRK2 (unknown origin) by NanoBRET cellular target engagement assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50563533(CHEMBL4777288)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of DYRK1B (unknown origin) by NanoBRET cellular target engagement assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50563533(CHEMBL4777288)
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of DYRK1A (unknown origin) by NanoBRET cellular target engagement assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDual specificity protein kinase CLK4(Human)
Masaryk University

Curated by ChEMBL
LigandPNGBDBM50563533(CHEMBL4777288)
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition of CLK4 (unknown origin) by NanoBRET cellular target engagement assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDual specificity protein kinase CLK3(Human)
Masaryk University

Curated by ChEMBL
LigandPNGBDBM50563533(CHEMBL4777288)
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of CLK3 (unknown origin) by NanoBRET cellular target engagement assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDual specificity protein kinase CLK2(Human)
Masaryk University

Curated by ChEMBL
LigandPNGBDBM50563533(CHEMBL4777288)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of CLK2 (unknown origin) by NanoBRET cellular target engagement assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
Masaryk University

Curated by ChEMBL
LigandPNGBDBM50563533(CHEMBL4777288)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CLK1 (unknown origin) by NanoBRET cellular target engagement assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHomeodomain-interacting protein kinase 2(Human)
Masaryk University

Curated by ChEMBL
LigandPNGBDBM50563533(CHEMBL4777288)
Affinity DataIC50: 119nMAssay Description:Inhibition of human recombinant HIPK2 using myelin substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Masaryk University

Curated by ChEMBL
LigandPNGBDBM50563533(CHEMBL4777288)
Affinity DataIC50: 248nMAssay Description:Inhibition of human recombinant HIPK1 using myelin substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50563533(CHEMBL4777288)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human full length recombinant DYRK2 using casein substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50563533(CHEMBL4777288)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human full length recombinant DYRK1B using RRRFRPASPLRGPP substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50563533(CHEMBL4777288)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human full length recombinant DYRK1A using RRRFRPASPLRGPP substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDual specificity protein kinase CLK4(Human)
Masaryk University

Curated by ChEMBL
LigandPNGBDBM50563533(CHEMBL4777288)
Affinity DataIC50: 1.47E+3nMAssay Description:Inhibition of human recombinant CLK4 using YRRAAVPPSPSLS substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDual specificity protein kinase CLK3(Human)
Masaryk University

Curated by ChEMBL
LigandPNGBDBM50563533(CHEMBL4777288)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human full length recombinant CLK3 using ERMRPRKRQGSVR substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDual specificity protein kinase CLK2(Human)
Masaryk University

Curated by ChEMBL
LigandPNGBDBM50563533(CHEMBL4777288)
Affinity DataIC50: 1.43E+3nMAssay Description:Inhibition of human recombinant CLK2 using YRRAAVPPSPSLSR substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
Masaryk University

Curated by ChEMBL
LigandPNGBDBM50563533(CHEMBL4777288)
Affinity DataIC50: 946nMAssay Description:Inhibition of human recombinant CLK1 using ERMRPRKRQGSVR substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed