BDBM50562112 CHEMBL4743888

SMILES CC1(C)C(=O)N(Cc2c(F)cccc2Cl)c2cc(ccc12)C(=O)NCc1c(F)cc(F)cc1F

InChI Key InChIKey=OEBVYNULNKSONR-UHFFFAOYSA-N

Data  3 EC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50562112   

TargetStimulator of interferon genes protein(Human)
Curadev Pharma

Curated by ChEMBL
LigandPNGBDBM50562112(CHEMBL4743888)
Affinity DataEC50:  185nMAssay Description:Activation of wild-type human STING expressed in HEK293T cells assessed as IRF3 reporter activation measured after 20 hrs by luciferase reporter gene...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetStimulator of interferon genes protein(Human)
Curadev Pharma

Curated by ChEMBL
LigandPNGBDBM50562112(CHEMBL4743888)
Affinity DataEC50:  185nMAssay Description:Agonist activity at human STINGMore data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetStimulator of interferon genes protein(Human)
Curadev Pharma

Curated by ChEMBL
LigandPNGBDBM50562112(CHEMBL4743888)
Affinity DataEC50:  185nMAssay Description:Agonist activity at human STING in HEK293T cells by luciferase cell based assayMore data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)