BDBM50561967 CHEMBL4763995

SMILES CSc1ccccc1C(=O)NCCCC[C@H](NC(=O)c1cncs1)c1ncc([nH]1)-c1ccc2ccccc2c1

InChI Key InChIKey=IBVNIPPBTCWYJG-UHFFFAOYSA-N

Data  12 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50561967   

TargetHistone deacetylase 4(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50561967(CHEMBL4763995)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of HDAC4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50561967(CHEMBL4763995)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant full length FLAG-tagged HDAC1 expressed in HEK293F cells using BML-KI104 as substrate in presence of SAHA as inhibito...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 2(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50561967(CHEMBL4763995)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of human recombinant full length FLAG-tagged HDAC2 expressed in baculovirus infected Sf9 cells using BML-KI104 as substrate in presence of...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 3(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50561967(CHEMBL4763995)
Affinity DataIC50: 29nMAssay Description:Inhibition of human recombinant full length FLAG-tagged HDAC3 expressed in HEK293F cells in using BML-KI104 as substrate in presence of SAHA as inhib...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50561967(CHEMBL4763995)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of human recombinant HDAC8 expressed in Escherichia coli using BML-KI178 as substrate and SAHA as inhibitor preincubated for 3 hrs followe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50561967(CHEMBL4763995)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of HDAC6 (unknown origin) using BML-KI104 as substrate in presence of SAHA as inhibitor preincubated for 3 hrs followed by addition of sub...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 11(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50561967(CHEMBL4763995)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human recombinant full length HDAC11 expressed in baculovirus expression system using Boc-Lys(TFA)-AMC as substrate in presence of SAHA...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50561967(CHEMBL4763995)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC10 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 9(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50561967(CHEMBL4763995)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of HDAC9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 7(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50561967(CHEMBL4763995)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of HDAC7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50561967(CHEMBL4763995)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human recombinant full length N-terminal GST tagged HDAC5 expressed in sf9 insect cells using Boc-Lys(TFA)-AMC as substrate in presence...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1/2/3/8(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50561967(CHEMBL4763995)
Affinity DataEC50: >4.00E+4nMAssay Description:Inhibition of class 1 HDAC in human Jurkat model of HIV latency assessed as reactivation of HIV latency incubated for 20 hrs in presence of SAHA and ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50561967(CHEMBL4763995)
Affinity DataIC50: 16nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed