BDBM50561527 CHEMBL4764481

SMILES [H][C@@]12CC[C@@]([H])(C1)[C@H](C2)Nc1nc(N)c(s1)C(=O)c1ccccc1[N+]([O-])=O

InChI Key InChIKey=JRNXAQINDCOHGS-UHFFFAOYSA-N

Data  9 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50561527   

TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50561527(CHEMBL4764481)
Affinity DataIC50: 138nMAssay Description:Inhibition of CDK1/cyclinB (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50561527(CHEMBL4764481)
Affinity DataIC50: 233nMAssay Description:Inhibition of CDK2/cyclinA (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50561527(CHEMBL4764481)
Affinity DataIC50: 367nMAssay Description:Inhibition of CDK2/cyclinE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 3/G1/S-specific cyclin-E1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50561527(CHEMBL4764481)
Affinity DataIC50: 399nMAssay Description:Inhibition of CDK3/cyclinE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50561527(CHEMBL4764481)
Affinity DataIC50: 112nMAssay Description:Inhibition of CDK4/cyclinD (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50561527(CHEMBL4764481)
Affinity DataIC50: 159nMAssay Description:Inhibition of CDK5/p35 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50561527(CHEMBL4764481)
Affinity DataIC50: 186nMAssay Description:Inhibition of CDK5/p25 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50561527(CHEMBL4764481)
Affinity DataIC50: 555nMAssay Description:Inhibition of CDK7/cyclinH/MAT1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50561527(CHEMBL4764481)
Affinity DataIC50: 5nMAssay Description:Inhibition of CDK9/cyclinT1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)