BDBM50557927 CHEMBL4788009
SMILES Cc1nc2nc(nn2c(C)c1CC(=O)Nc1cccc(c1)C(F)(F)F)-c1cccnc1
InChI Key InChIKey=MTJCWZPTCSKXKK-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50557927
Affinity DataIC50: 39nMAssay Description:Inhibition of human TRKA kinase domain by HTRF KinEASE biochemical assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of human TRKA by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of human TRKB by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 102nMAssay Description:Inhibition of human TRKA at inactive state assessed as inhibition of substrate phosphorylation using fluorescently-labelled peptide as substrate by c...More data for this Ligand-Target Pair
Affinity DataIC50: 950nMAssay Description:Inhibition of human TRKA at active state assessed as inhibition of substrate phosphorylation using fluorescently-labelled peptide as substrate by cal...More data for this Ligand-Target Pair
Affinity DataKi: 66nMAssay Description:Inhibition of human TRKA at inactive state by kinetic based analysisMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of human TRKA at active state by kinetic based analysisMore data for this Ligand-Target Pair