BDBM50556846 CHEMBL4781400

SMILES NS(=O)(=O)c1ccc(NS(=O)(=O)CCNC(=O)Nc2ccc(F)cc2)cc1

InChI Key InChIKey=RNTJUUSYPCOMRZ-UHFFFAOYSA-N

Data  6 KI

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50556846   

TargetCarbonic anhydrase 9(Human)
Ege University

Curated by ChEMBL
LigandPNGBDBM50556846(CHEMBL4781400)
Affinity DataKi:  8.80nMAssay Description:Inhibition of recombinant human carbonic anhydrase 9 incubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red-based stopped-f...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 12(Human)
Ege University

Curated by ChEMBL
LigandPNGBDBM50556846(CHEMBL4781400)
Affinity DataKi:  44nMAssay Description:Inhibition of recombinant human carbonic anhydrase 12 incubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red-based stopped-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 7(Human)
Ege University

Curated by ChEMBL
LigandPNGBDBM50556846(CHEMBL4781400)
Affinity DataKi:  311nMAssay Description:Inhibition of recombinant human carbonic anhydrase 7 incubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red-based stopped-f...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 4(Human)
Ege University

Curated by ChEMBL
LigandPNGBDBM50556846(CHEMBL4781400)
Affinity DataKi:  404nMAssay Description:Inhibition of recombinant human carbonic anhydrase 4 incubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red-based stopped-f...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ege University

Curated by ChEMBL
LigandPNGBDBM50556846(CHEMBL4781400)
Affinity DataKi:  458nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 incubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red-based stopped-f...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 1(Human)
Ege University

Curated by ChEMBL
LigandPNGBDBM50556846(CHEMBL4781400)
Affinity DataKi:  714nMAssay Description:Inhibition of recombinant human carbonic anhydrase 1 incubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red-based stopped-f...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed