BDBM50554034 CHEMBL4747269

SMILES Nc1cc([C@H](CCN[C@H]2C[C@H](c3ccccc23)c2ccccc2)c2ccccc2)c2nn[nH]c2n1

InChI Key InChIKey=PUZMDZNRNPQCRQ-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50554034   

TargetMyeloperoxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50554034(CHEMBL4747269)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of PMA-induced MPO in human Neutrophil incubated for 3 mins by luminometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetMyeloperoxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50554034(CHEMBL4747269)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 120 mM NaCl by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetLactoperoxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50554034(CHEMBL4747269)
Affinity DataIC50: 6.20E+4nMAssay Description:Inhibition of LPO (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEosinophil peroxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50554034(CHEMBL4747269)
Affinity DataIC50: 92nMAssay Description:Inhibition of human EPX bromination activity using tyrosine as substrate by measuring 3-bromo tyrosine formation incubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed