BDBM50553819 CHEMBL4755149
SMILES COc1ccc(cc1)-n1nnc2cnc(N[C@@H]3CCN(C3)c3ccncc3)nc12
InChI Key InChIKey=GDSSVNNRCKMPPZ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50553819
Affinity DataKd: 170nMAssay Description:Binding affinity to wild-type human partial length ERK3 (M1 to P413 residues) expressed in bacterial expression system by kinomescan methodMore data for this Ligand-Target Pair
Affinity DataIC50: 93nMAssay Description:Inhibition of recombinant His6-GST fusion tagged ERK3 (1 to 365 residues) (unknown origin) expressed in Sf21 insect cells using MK5 K51A mutant as su...More data for this Ligand-Target Pair
Affinity DataIC50: 78nMAssay Description:Inhibition of recombinant His6-GST fusion tagged ERK3 (1 to 471 residues) (unknown origin) expressed in Sf21 insect cells using MK5 K51A mutant as su...More data for this Ligand-Target Pair
Affinity DataIC50: 73nMAssay Description:Inhibition of recombinant full length His6-GST fusion tagged ERK3 (1 to 721 residues) (unknown origin) using MK5 K51A mutant as substrate by ADP-Glo ...More data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Inhibition of ERK3 (unknown origin) expressed in HEK293 cells cotransfected with nano-luciferase by NanoBRET assayMore data for this Ligand-Target Pair