BDBM50549944 CHEMBL4747073

SMILES O=C1NCc2c(c[nH]c12)-c1cnc2[nH]cc(Cc3ccccc3)c2c1

InChI Key InChIKey=QHODOVGQIJJDRT-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50549944   

TargetHepatocyte growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50549944(CHEMBL4747073)
Affinity DataKd:  5.30E+3nMAssay Description:Binding affinity to folded P-loop conformation of wild type N-terminal NH-tagged and avi-tagged dephosphorylated human c-MET (956 to 1390 residues) e...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50549944(CHEMBL4747073)
Affinity DataIC50: 660nMAssay Description:Inhibition of wild type N-terminal NH-tagged and avi-tagged dephosphorylated human c-MET (956 to 1390 residues) expressed in Sf21 cells using poly (G...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50549944(CHEMBL4747073)
Affinity DataIC50: 2.19E+4nMAssay Description:Inhibition of c-Met phosphorylation at Tyr 1234/Tyr1235 residues in human NCI-H1993 cells incubated for 4 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed