BDBM50549809 BMS-205603-01::CHEBI:17568::Fluorouracil specified compound c::Hybar x::Lamivudine impurity e::Lamivudine impurity e rs::NSC-3970::Pyrod::SQ-6201::SQ-7726::SQ-8493::Uracil

SMILES O=c1cc[nH]c(=O)[nH]1

InChI Key InChIKey=ISAKRJDGNUQOIC-UHFFFAOYSA-N

Data  2 KI  1 IC50

PDB links: 71 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50549809   

TargetProtein cereblon(Human)
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50549809(SQ-8493 | Fluorouracil specified compound c | SQ-7...)
Affinity DataIC50: 4.15E+5nMAssay Description:Binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by measuring baseline corrected normalized fluorescence by MS...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein cereblon(Human)
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50549809(SQ-8493 | Fluorouracil specified compound c | SQ-7...)
Affinity DataKi:  3.50E+4nMAssay Description:Binding affinity to CRBN (unknown origin) assessed as inhibition constant by FRET assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProtein cereblon(Human)
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50549809(SQ-8493 | Fluorouracil specified compound c | SQ-7...)
Affinity DataKi:  2.12E+5nMAssay Description:Binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by measuring baseline corrected normalized fluorescence by MS...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed