BDBM50545912 CHEMBL4749664
SMILES Cc1noc(C)c1-c1ccc2nc(nc(N3CCOC[C@@H]3c3ccccc3)c2c1)-c1cnn(CC(C)(C)O)c1
InChI Key InChIKey=SUFVOUWYHJXPBW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 50545912
Affinity DataKd: 70nMAssay Description:Competitive binding affinity to human partial length BRD4 (BD1,2) (N44 to E460 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
National Institutes of Health
Curated by ChEMBL
National Institutes of Health
Curated by ChEMBL
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of human ERG by manual patch clamp assayMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human full-length recombinant N-terminal His-tagged BRD4 (2 to 1362 residues) expressed in Sf9 cells using histone H4 peptide containin...More data for this Ligand-Target Pair
Affinity DataKd: 45nMAssay Description:Binding affinity to human partial length BRD2 (BD1) (K71 to N194 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 87nMAssay Description:Binding affinity to human partial length BRD2 (BD1,2) (K71 to D455 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 200nMAssay Description:Binding affinity to human partial length BRD2 (BD2) (E348 to D455 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 11nMAssay Description:Binding affinity to human partial length BRD3 (BD1) (P24 to E144 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 29nMAssay Description:Binding affinity to human partial length BRD3 (BD1,2) (P24 to P416 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 44nMAssay Description:Binding affinity to human partial length BRD3 (BD2) (G306 to P416 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 17nMAssay Description:Binding affinity to human partial length BRD4 (BD1) (N44 to E168 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 81nMAssay Description:Binding affinity to human partial length BRD4 (BD2) (K333 to E460 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 76nMAssay Description:Binding affinity to human partial length BRDT (BD1) (N21 to E137 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 160nMAssay Description:Binding affinity to human partial length BRDT (BD2) (K250 to E382 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 170nMAssay Description:Binding affinity to human partial length BRDT (BD1,2) (N21 to E382 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair