BDBM50537598 CHEMBL4646628::US11149020, Compound 1 (MW-181)
SMILES CN(C)c1cc(-c2ccncc2)c(nn1)-c1cccc2ccccc12
InChI Key InChIKey=GEAPHVHHVPDTKQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50537598
TargetMitogen-activated protein kinase 14(Human)
The Trustees of Columbia University In The City of New York
US Patent
The Trustees of Columbia University In The City of New York
US Patent
Affinity DataIC50: 215nMAssay Description:The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...More data for this Ligand-Target Pair
TargetCasein kinase I isoform delta(Human)
The Trustees of Columbia University In The City of New York
US Patent
The Trustees of Columbia University In The City of New York
US Patent
Affinity DataIC50: 1.00E+4nMAssay Description:The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Human)
The Trustees of Columbia University In The City of New York
US Patent
The Trustees of Columbia University In The City of New York
US Patent
Affinity DataIC50: 190nMAssay Description:Inhibition of human p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 410nMAssay Description:Inhibition of human p38betaMore data for this Ligand-Target Pair
TargetCasein kinase I isoform delta(Human)
The Trustees of Columbia University In The City of New York
US Patent
The Trustees of Columbia University In The City of New York
US Patent
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CK1deltaMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Human)
The Trustees of Columbia University In The City of New York
US Patent
The Trustees of Columbia University In The City of New York
US Patent
Affinity DataKi: 180nMAssay Description:Inhibition of human p38alphaMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Human)
The Trustees of Columbia University In The City of New York
US Patent
The Trustees of Columbia University In The City of New York
US Patent
Affinity DataKi: 184nMAssay Description:The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...More data for this Ligand-Target Pair
Affinity DataKi: 320nMAssay Description:Inhibition of human p38betaMore data for this Ligand-Target Pair