BDBM50536213 CHEMBL1703303

SMILES CS(=O)(=O)Nc1cccc2[nH]ncc12

InChI Key InChIKey=CAMWAWBWBXRPRP-UHFFFAOYSA-N

Data  3 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50536213   

TargetTyrosine-protein kinase JAK2(Human)
Leo Pharma

Curated by ChEMBL
LigandPNGBDBM50536213(CHEMBL1703303)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human His-tagged JAK2 expressed in baculovirus using biotin-synthetic peptide as substrate by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase JAK2(Human)
Leo Pharma

Curated by ChEMBL
LigandPNGBDBM50536213(CHEMBL1703303)
Affinity DataKd:  1.26E+4nMAssay Description:Inhibition of human His-tagged JAK2 expressed in baculovirus using biotin-synthetic peptide as substrate by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase JAK1(Human)
Leo Pharma

Curated by ChEMBL
LigandPNGBDBM50536213(CHEMBL1703303)
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of human Gst-tagged JAK1 (850 to 1154 residues) expressed in baculovirus using biotin-synthetic peptide as substrate after 40 mins by HTRF...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Leo Pharma

Curated by ChEMBL
LigandPNGBDBM50536213(CHEMBL1703303)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human Gst-tagged JAK1 (850 to 1154 residues) expressed in baculovirus using biotin-synthetic peptide as substrate after 40 mins by HTRF...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed