BDBM50535218 CHEMBL4588676

SMILES CC(=O)N1CCc2nc(NC3Cc4ccccc4C3)ncc2C1

InChI Key InChIKey=YZUQRESBRMOGBQ-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50535218   

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50535218(CHEMBL4588676)
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of autotaxin in healthy human plasma assessed as reduction in LPA level after 3 hrs by mass spectrometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50535218(CHEMBL4588676)
Affinity DataIC50: 520nMAssay Description:Inhibition of recombinant full length human C-terminal His-tagged autotaxin expressed in human 293E cells assessed as choline release using lysophosp...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)