BDBM50532270 CHEMBL1236215

SMILES CSc1nc2ccccc2c(=O)n1-c1c(F)cccc1F

InChI Key InChIKey=BFNBJSXMXXQLAW-UHFFFAOYSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50532270   

TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50532270(CHEMBL1236215)
Affinity DataIC50: 510nMAssay Description:Inhibition of recombinant human PDE7A1 catalytic domain (130 to 482 residues) expressed in Escherichia coli BL21-CodonPlus cells using [3H]cAMP as su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50532270(CHEMBL1236215)
Affinity DataIC50: 510nMAssay Description:Inhibition of recombinant human PDE7A1 catalytic domain (130 to 482 residues) expressed in Escherichia coli BL21-CodonPlus cells using [3H]cAMP as su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
University of Louisiana At Lafayette

Curated by ChEMBL
LigandPNGBDBM50532270(CHEMBL1236215)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of PDE4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50532270(CHEMBL1236215)
Affinity DataIC50: 510nMAssay Description:Inhibition of PDE7A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
University of Louisiana At Lafayette

Curated by ChEMBL
LigandPNGBDBM50532270(CHEMBL1236215)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of PDE4D2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed