BDBM50528959 CHEMBL4465849

SMILES Nc1nc2[nH]cc(Cc3ccc(cc3)C(=O)Nc3ccccc3CCC(O)=O)c2c(=O)[nH]1

InChI Key InChIKey=PABYCMRDFQGQKT-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50528959   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Cryptosporidium parvum)
Yale University

Curated by ChEMBL
LigandPNGBDBM50528959(CHEMBL4465849)
Affinity DataIC50: 1.14E+5nMAssay Description:Inhibition of recombinant Cryptosporidium hominis TS-DHFR expresssed in Escherichia coli PA414 using dUMP and 5,10-methylenetetrahydrofolate as subst...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50528959(CHEMBL4465849)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of recombinant human His6-tagged TS using dUMP and 5,10-methylenetetrahydrofolate as substrate by spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed