BDBM50520130 CHEMBL4435250

SMILES COc1cc(CNC(=O)c2cc(Cn3ccn(C)c3=N)cc(c2)-c2ccc(F)cc2C)cc(OC)c1

InChI Key InChIKey=PSABMKXBOJUOBD-UHFFFAOYSA-N

Data  1 KI  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50520130   

TargetWD repeat-containing protein 5(Human)
Frederick National Laboratory For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50520130(CHEMBL4435250)
Affinity DataKd:  0.0490nMAssay Description:Competitive inhibition of human N-terminal His6-SUMO tagged WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold(DE3) cells using 10-mer...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetWD repeat-containing protein 5(Human)
Frederick National Laboratory For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50520130(CHEMBL4435250)
Affinity DataKi:  0.0490nMAssay Description:Inhibition of 6His-SUMO tagged human WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold (DE3) cells incubated for 1 hr by TR-FRET assa...More data for this Ligand-Target Pair
In DepthDetails
PubMed