BDBM50519616 CHEMBL4449176
SMILES OC(=O)c1ccc2OC[C@]3(CCc4cc(Cl)ccc34)CN(CC3CCC3)c2c1
InChI Key InChIKey=YLXRDIJLTBHLLJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50519616
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Caen Normandy
Curated by ChEMBL
University of Caen Normandy
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of TAMRA-labeled BIM BH3 peptide binding to human Mcl1 (171 to 327 residues) incubated for 120 mins by fluorescence polarizationMore data for this Ligand-Target Pair
3D Structure (crystal)TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Caen Normandy
Curated by ChEMBL
University of Caen Normandy
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant His6-tagged human MCL1 (171 to 327 residues) expressed in Escherichia coli and TAMRA labeled Bim BH3 peptide interaction us...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Caen Normandy
Curated by ChEMBL
University of Caen Normandy
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of MCL1 (unknown origin)More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Caen Normandy
Curated by ChEMBL
University of Caen Normandy
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of TAMRA-labeled BIM-BH3 peptide binding to 6His-tagged human recombinant Mcl-1 (171 to 327 residues) incubated for 120 mins by fluorescen...More data for this Ligand-Target Pair