BDBM50519045 CHEMBL4436725

SMILES CCc1sc2ncnc(N[C@H](Cc3ccccc3)C(O)=O)c2c1-c1cccc2[nH]ccc12

InChI Key InChIKey=IZDAFHXFYWJQKU-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50519045   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50519045(CHEMBL4436725)
Affinity DataKi:  5.70E+3nMAssay Description:Displacement of N-terminal fluorescein labelled Puma-BH3 peptide from TEV-fused His-tagged human Mcl-1 expressed in Escherichia coliBL21(DE3) pLysS c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50519045(CHEMBL4436725)
Affinity DataKi:  5.70E+3nMAssay Description:Displacement of N-terminal fluorescein labelled Puma-BH3 peptide from TEV-fused His-tagged human Mcl-1 expressed in Escherichia coliBL21(DE3) pLysS c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl-2-like protein 1(Human)
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50519045(CHEMBL4436725)
Affinity DataKi:  1.35E+5nMAssay Description:Inhibition of Bcl-XL (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed